1,3-diformylazulene was synthesized by 1,3-dibromoazulenes, organic base and catalyst under 6×10⁶ Pa at 120 ℃ with carbon monoxide-hydrogen for the formylation reagent, while palladium(Ⅱ) was as the catalyst，benzene as solvent. The yield was 77% under the condition the molar ratio of 1,3-dibromoazulenes,organic base and catalyst was 1∶2∶0.02. Based on the reaction, by changing the substituent, 1,3 - dimethylacyl-5-methyl azulene, 1,3-dimethylacyl-6-tert-butyl-azulene, 1,3-diformy-2,4,6-trimethyl-azulene were synthesized by acylation reactions, the yields were 68%, 60%, 65%. This method provides several advantages such as good yields, simple work-up procedures and mild conditions. All the products are confirmed by 1H-NMR, IR spectra and elemental analysis.

Azulene,   ,  1,3-Diformylazulene,    , Carbon monoxide-hydrogen,    ,  Palladium catalyst,    ,  Synthesis