Abstract:        The matching relationship between the size of SMG-mm crosslinked polymer microspheres and the pore size of the nuclear membrane was studied by filtration experiments. The results show that the plugging effect of the microspheres with different pore sizes is very different, and there is a membrane pore size matched with the size of the microspheres. When the concentration and membrane pore size are the same, the pressure has a significant effect on the filtration results. In a certain concentration range, with the increase of concentration of microspheres dispersed system and filtration pressure, plugging effect is better. While when the concentration exceeds the optimum value, the performance of the plugging effect is more terrible; SEM observation results show that the effective plugging can be formed when the diameter of the microspheres and the pore size of the membrane are the best match.

Key words: Submillimeter, Crosslinkedpolymermicrospheres, Nucleoporemembrane, Plugging

摘要：       通过过滤实验对SMG-mm 交联聚合物微球的大小和核孔膜孔径的匹配关系进行研究。结果表明,SMG-mm 微球分散体系对不同孔径的核孔膜的封堵效果差异很大,特定压力下存在一个与微球大小匹配最好的膜孔径;当质量浓度和膜孔径相同时,压力对微球的过滤结果有显著影响;在一定的质量浓度范围内,随着微球分散体系的质量浓度和过滤压力增加,封堵效果越好,但是当质量浓度超过最佳值后,封堵效果变差;SEM 观测结果表明,微球粒径与核孔膜孔径最佳匹配时才能形成有效的封堵。

关键词: 亚毫米, 交联聚合物微球, 核孔膜, 封堵