Abstract: In this paper, methyl bromoacetate and triphenylphosphine were used as starting materials. First, bromophosphorus salt was prepared, and then alkali was added to prepare Wittig reagent. Preparation of α,β⁃unsaturated carboxylic acid ester (methyl cinnamate) by Wittig reaction using benzaldehyde and Wittig reagent The results show that the optimal conditions for the reaction are: Wittig reagent and benzaldehyde are used as raw materials, benzene is used as a solvent, and potassium carbonate is added as an additive. The reaction is stirred at room temperature for 24 hours, and the final product methyl cinnamate is obtained in a higher yield (86%). At the same time, the configuration of the product is a trans olefin product, indicating that the method has good stereoselectivity.

Key words: Wittig reagent, Wittig reaction, α,β?Unsaturated carboxylic acid ester, Methyl cinnamate

摘要： 以溴乙酸甲酯和三苯基膦为起始原料，首先制备溴磷盐，再加入碱，顺利地制得了Wittig试剂。利用苯甲醛和Wittig试剂发生Wittig反应制得α,β⁃不饱和羧酸酯（肉桂酸甲酯）。结果表明，最佳反应条件为：Wittig试剂和苯甲醛作为原料，苯作为溶剂，同时加入碳酸钾作为添加剂，在常温下搅拌反应24 h，以较高的收率（86%）得到了最终产物肉桂酸甲酯。同时，产物的构型为反式烯烃，说明了此方法具有较好的立体选择性。

关键词: Wittig试剂, 　Wittig反应, 　α,β?不饱和羧酸酯, 　肉桂酸甲酯