季铵盐类相转移催化法合成苯甲酸苄酯

辽宁石油化工大学学报 ›› 2007, Vol. 27 ›› Issue (4): 21-23.

季铵盐类相转移催化法合成苯甲酸苄酯

陈珊珊, 时维振

辽宁石油化工大学职业技术学院, 辽宁抚顺113001

收稿日期:2007-05-29 出版日期:2007-12-20 发布日期:2017-07-05
作者简介:陈珊珊(1980 -), 女, 黑龙江鹤岗市, 在读硕士

Synthesis of Benzyl Benzoate Catalyzed by Quaternary Ammonium Salt as Phase Transfer Catalyst

Vocationa l and Technical College , Liaoning Univ ersity o f Petroleum & Chemical Technology ,Fushun Liaoning 113001 , P .R .China

Received:2007-05-29 Published:2007-12-20 Online:2017-07-05

摘要/Abstract

摘要： 研究了由苯甲酸钠和氯化苄通过相转移催化法合成苯甲酸苄酯的亲核取代反应, 考察了几种季铵盐类相转移催化剂的亲核取代反应催化活性。筛选出合成苯甲酸苄酯反应催化活性较好的一种季铵盐类相转移催化剂四丁基碘化铵((C₄ H₉)₄ NI), 在n(苯甲酸钠)/n(氯化苄)为1 .0 ∶1 .3 , 反应温度110 ℃, 反应时间2 .5 ～ 3 .0 h, n(催化剂)/ n(苯甲酸钠)为0.06 , 体系pH 值为5 ～ 6 时, 苯甲酸苄酯的收率可达90%以上。

关键词: 苯甲酸苄酯, 　相转移催化剂, 　反应条件, 　季铵盐

Abstract:

The nucleophilic substitution reaction of producing benzy l benzoate by sodium benzoate and benzyl chloride in phase transfer catalysis process was studied .The catalytic performances of sever alquaternary ammonium salts as the phase -transfer catalyst were examined , and found that phase transfer catalyst((C4H 9)4 NI)was the preferred one , the yield of be nzyl benzoate would be up to more than 90 % under the conditions as follows :n(sodium benzoate)/ n(benzy l chloride)=1 .0 ∶1.3, temperature of 110 ℃, reaction time of 2 .5 ～ 3.0 h , moleratio of catalyst and so diumbenzoate 0 .06 and pH value between 5 and 6.

Key words: 　Benzy l benzoate, , Phase transfer catalyst, , Reaction condition, , Quaternary ammonium salt

陈珊珊, 时维振. 季铵盐类相转移催化法合成苯甲酸苄酯[J]. 辽宁石油化工大学学报, 2007, 27(4): 21-23.

CHEN Shan -shan,SHI Wei -zhen. Synthesis of Benzyl Benzoate Catalyzed by Quaternary Ammonium Salt as Phase Transfer Catalyst[J]. Journal of Liaoning Petrochemical University, 2007, 27(4): 21-23.