Metal-organic Frameworks MIL-53(Al) has been hydrothermally synthesized and investigated by means of X-ray diffraction (XRD) and N2 adsorption-desorption experiment. Adsorption isotherms of C8 aromatic isomers, including para-xylene, ortho-xylene, meta-xylene, and ethylbenzene, in metal-organic framework Mil-53(Al) has been systematically investigated by using intelligent gravimetric analyzer (IGA) at 303 K and 373 K. The results indicate that adsorption isotherms at 303 K present type-I isotherms. The deviation from normal Langmuir model of the isotherms at 373 K can be, however, found because of the breathing effect of Mil-53(Al) framework. The results also indicate that o-xylene in this material has very good adsorption capacity, while effect of ethylbenzene adsorption is the worst. Two-component mixture separation factor can be obtained through the fixed bed breakthrough experiments and gas chromatography analysis. It has good separation performance of o-xylene and ethylbenzene, and selectivity achieved to 9.2. 

Mesoporous materials SBA-15 and SBA-15-NH2 were investigated as the water-insoluble aspirin carrier for controlled drug delivery. The samples structure，drug loading and release profiles were characterized by means of Fourier transform infrared spectroscopy (FT-IR) and UV-spectrophotometer(UV), meantime the release kinetics were analyzed using following mathethematical models Korsmeyer-Peppas equation and Higuchi equation. The results show that the adsorption capacity and release properties of SBA-15 for drug molecules can be improved by functionalizing its surfaces with amine groups, the adsorption of aspirin from 14.2% to 19.5%. The release process of SBA-15-Aspirin follow a Fickian diffusion mechanism, and SBA-15-NH2-Aspirin follow a Non-Fickian diffusion mechanism.

A series of polyhalogenated biphenyls have been used to develop quantitative structure-retention relationship for their gas and liquid chromatographic retention index by using two 2D descriptors of the atom type electrotopogical state index and the molecular electronegativity distance vector based on 13 atomic types. QSRR of 55 kinds of polyhalogenated biphenyls models were built by multiple liner regression and artificial neural network. The results show that using artificial neural network method is better than [KG*4]using [KG*4]multivariate [KG*4]linear [KG*4]regression, the [KG*4]predictive [KG*4]correlation [KG*4]coefficient R can reach above 0.99. It is demonstrated that using artificial neural network method can accurately predict polyhalogenated biphenyls gas and liquid chromatographic retention index.

Mesoporous SBA-15 materials were functionalized with amine groups through postsynthesis, and resulting functionalized material was investigated as matrix for controlled drug delivery. The structure, composition and framework of the material were investigated by means of X-ray diffraction (XRD), intelligent weight analyzer (IGA), transmission scanning electron microscopy (TEM), infrared spectrometer (IR), and molecular simulation software. Ibuprofen (IBU) was selected as model drug and loaded onto the unmodified and functionalized SBA-15. It was revealed that the adsorption capacities and release behaviors of this model drug were highly dependent on the surface properties of SBA-15 materials. The release rate of IBU from SBA-15 functionalized by postsynthesis is found to be effectively controlled as compared to that from pure SBA-15 due to the ionic interaction between carboxyl groups in IBU and amine groups on the surface of SBA-15.

Three-dimensional network structure of the metal-organic frameworks(MOFs), MIL-53(Cr)as and MIL-53(Al)as, was hydrothermally synthesized by heating a mixture of 1,4-benzenedicarboxylic acid(H2BDC), water, chromium nitrate, and aluminum nitrate for three days at 220 ℃. The samples were then calcinated at 300 ℃ and 330 ℃, respectively, to obtaine MIL-53(Cr)ht and MIL-53(Al)ht. The structure, composition and hydrogen storage properties of the materials were investigated by means of X-ray diffraction (XRD), intelligent weight analyzer (IGA), scanning electron microscopy (SEM), infrared spectrometer (IR) and thermal gravimetric analysis (TG). The results show that the unique breathing effect of the metal-organic frameworks MIL-53, especially the MIL-53(Al)ht which possesses a high surface area, large pore volume and diameter, makes a beter hydrogen absorption performance.