单模聚焦微波辐射合成对羟基苯甲酸正丁酯

辽宁石油化工大学学报 ›› 2005, Vol. 25 ›› Issue (2): 23-25.

单模聚焦微波辐射合成对羟基苯甲酸正丁酯

侯金松, 李丽华, 张金生^＊

辽宁石油化工大学石油化工学院, 辽宁抚顺113001

收稿日期:2004-11-04 出版日期:2005-06-20 发布日期:2017-04-18
作者简介:侯金松(1978 -), 男, 安徽来安县, 在读硕士。

Synthesis of n -Butyl p -Hydroxybenzoate Under Single -Mode Focused Microwave I rradiation

School of Petrochemical Technology , Liaoning University of Petroleum & Chemical Technology ,
Fushun Liaoning 113001 , P .R .China

Received:2004-11-04 Published:2005-06-20 Online:2017-04-18

摘要/Abstract

摘要： 　利用Discov er 微波精确有机合成系统, 采用单膜聚焦微波辐射技术及电脑微控和空压气体同步冷却技术, 以一水合硫酸氢钠为催化剂, 研究了对羟基苯甲酸正丁酯的合成。考察了催化剂质量、微波辐射功率和时间及反应物料配比对产率的影响。在优化的合成条件下:n(正丁醇)/ n(对羟基苯甲酸)/ n(一水合硫酸氢钠)=0.15∶0.05∶0.005 8 , 辐射功率为210 W, 辐射时间为28 min , 反应产率达93.6 %。产品经傅立叶红外光谱仪及熔点仪表征, 证实与目标产物完全一致。

关键词: 　聚焦微波辐射, 　硫酸氢钠, 　对羟基苯甲酸正丁酯, 　酯化

Abstract:

Using Discover microwave organic chemistry rigour system , single -mode focused microwave irradiation technology and micro computer control, n -butyl p -hydroxybenzoate was synthesized with sodium bisulfate mono hydrate as catalyst .The reaction was cooled by constringent air at the same time .The effects of the mass of catalyst , the microwave power , time and the ratio of p hydroxy benzonic acid to n -butyl alcohol on the yield were investigated.Under optimal reaction conditions :n(n -butyl alcohol)/ n (p -hydro xybenzonic acid)/ n(sodium bisulfate)is 0 .15∶0 .05∶0.005 8 , irradiation power is 210 W and irradiation time is 28 minutes , the yield of ester is 93 .6 %.The product w as characterized by FT-IR spectrum and melting point determination .Product is consistent with the target product .

Key words: 　Focused microwave irradiation , Sodium bisulfate , n -Butyl p -hydroxy benzoate , Esteritication

侯金松, 李丽华, 张金生. 单模聚焦微波辐射合成对羟基苯甲酸正丁酯[J]. 辽宁石油化工大学学报, 2005, 25(2): 23-25.

HOU Jin -song,LI Li -hua,ZHANG Jin -sheng. Synthesis of n -Butyl p -Hydroxybenzoate Under Single -Mode Focused Microwave I rradiation[J]. Journal of Liaoning Petrochemical University, 2005, 25(2): 23-25.

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