Aiming at the problems of conventional temporary plugging materials in horizontal shale gas wells in Sichuan, such as insignificant increase in temporary plugging pressure, easy shedding under low pressure difference and poor plugging effect, long‑acting and short‑acting temporary plugging knots for perforation plugging were prepared. Their degradation performance and pressure‑bearing plugging performance were evaluated, the influence of injection method on plugging efficiency was explored, and a temporary plugging knot injection device was developed, thus forming a knot‑based temporary plugging fracturing technology for shale gas. The results show that in polymer slick‑water fracturing fluid at 90 ℃, the degradation rate of long‑acting temporary plugging knots is less than 10% within 83 h and more than 99% after 174 h, while that of short‑acting temporary plugging knots is less than 10% within 5 h and more than 99% after 24 h. Both types of temporary plugging knots exhibit static pressure‑bearing capacity higher than 50.0 MPa and dynamic plugging efficiency above 90%. The maximum single injection capacity of the device is 60 temporary plugging knots with a size of 18~20 mm, and the injection rate is adjustable from 1 to 60 knots per minute. Field tests were carried out in Well Ning‑A, a horizontal shale gas well, including 5 stages of inter‑stage temporary plugging and 6 stages of intra‑stage temporary plugging in casing‑deformed intervals. The average post‑plugging pressure increases were 9.0 MPa and 5.6 MPa, respectively. Field microseismic monitoring shows obvious differences in event points before and after temporary plugging, verifying the effectiveness of the proposed technology.