To ensure the effect of several rounds of profile control in Bohai oilfield, the adaptability of a drag-increasing in-situ gel profile control agent was investigated specifically in the study. The gelation property, thermal stability and micromorphology after gelation were measured by viscosimetry, rheological analysis and scanning electron microscope respectively. The injectivity, plugging property, selectivity and enhanced oil recovery effect of the profile control agent were investigated by sand packing experiments. The results show that the profile control agent has low initial viscosity, excellent injectability and deep migration performance, and weak chromatographic separation behavior in the reservoir. At the reservoir temperature of 65 ℃, it has a long gelation time, high gelation viscosity and good thermal stability. After gelation, it has a three-dimensional network structure with microspheres as cross-linked nodes inside, and demonstrates shear thickening characteristic at a shear rate of 4~12 s?1. Additionally, the profile control agent possesses excellent selective plugging performance and preferentially enters the breakthrough area to form plugging, , while maintaining a low oil plugging rate in the oil layers. The profile control agent shows a significant effect on enhancing oil recovery and the increase in crude oil recovery rate reaches 15.0%~23.0% after injecting 1.000 pore volume (PV). Generally, the drag-increasing in-situ gel profile control agent can adapt to the reservoir characteristics of Bohai offshore oilfield well, and realize in-depth profile control in the reservoir.