Aiming at the problems such as the large decline in water flooding production, the poor utilization of reservoirs, and the low formation pressure in the development of North First and Second Section West, the potential of well pattern adjustment in this area was studied. Combined with several reasons that affect the development effect of the block, it is analyzed that it is difficult to effectively improve the overall development status of the block by relying only on regular dynamic adjustment measures. Through the implementation of layered well pattern adjustment, the daily production volume of the entire area is increased by 5 640 t and the daily oil production is increased by 197 t. The water content was basically stable, the oil production rate rose to 0.60%, the flow pressure subsidence was restored, and the overall development of the block was effectively improved. As of August 2017, it has accumulatively increased oil by 20.5×104 t, and it is expected to increase oil recovery by more than 2.0 percentage points. Well network encryption and subdivision layer system adjustments have achieved significant effects, which solved the problem of poor level of use and improved the ultimate recovery rate.