Basic particle swarm algorithms were intelligentized. Based on the intelligentized algorithms and MATLAB, simulation regarding optimization of benzene-toluene flash vaporization process during process of chemical production was made. The simulation result shows that the amount of benzene in vapor phase product reaches the maximum under the condition of effective adjustment of temperature, pressure and diffluence coefficient and the production process is optimized. It also proves that the intelligentized algorithms are practical in optimization of chemical production process.