Solid superacid catalyst S₂O {}_{\mathrm{8}}^{\mathrm{2}-} /ZrO₂?CeO₂ was prepared by precipitation impregnation method using zirconium nitrate and cerium nitrate as metal sources.n?Butyl acetate was synthesized through the catalytic esterification of acetic acid and n?butanol over S₂O {}_{\mathrm{8}}^{\mathrm{2}-} /ZrO₂?CeO₂.The effects of catalyst mass,n(alkanol)/n(acid),reaction temperature and reaction time on the catalytic reaction were investigated.The catalyst was characterized by XRD,FT?IR,N₂ adsorption?desorption isotherm and NH₃?TPD.The results indicated that S₂O {}_{\mathrm{8}}^{\mathrm{2}-} /ZrO₂?CeO₂ possesses strong acidity and exhibits superior catalytic activity.The optimal reaction conditions were determined as follows: cerium loading（mass fraction） of 2.0%,catalyst mass of 0.6 g,n(alcohol)/n(acid) molar ratio of 2.0∶1.0,reaction temperature of 115 °C,reaction time of 4.0 h,and ammonium persulfate concentration of 0.5 mol/L.Under these optimal conditions,the esterification rate of n?butyl acetate reached 99.6%.After 5 cycles of repeated use,the conversion rate remained at 59.4%.