The high viscosity of heavy oil and studies the effect of construct and combination of oil-soluble viscosity reducer on viscosity reducing effect were discussed. The results show that unary-polymer has viscosity action and poor viscosity reducing effect, binary-polymer has definite raise and viscosity reducing rate exceeds 30% in 20 ℃, terpolymer containing twain or more polar functional group researches has preferable effect and viscosity reducing rate is concordant with 70% in 20 ℃, and advisable combination in difference viscosity reducer can display synergism and raise the viscosity reducing effect obviously.