Poly (arylpiperidine) anion exchange membrane (AEM) has been widely studied in anion exchange membrane fuel cells (AEMFCs) and alkaline electrolyzed water due to their excellent alkali resistance and stability. In this work, poly (triphenyl fluorene piperidine) (PTDP) AEM was prepared from 9,9?diphenylfluorene monomer with distorted large volume structure, and hydrophilic large volume cyclodextrin crosslinking agent (β?CD?Br₇) was introduced on this basis, which can control the microphase separation structure in AEMs. The prepared qPTDP?10?CD₅ AEM with 5% crosslinker content reached a high conductivity (130.2 mS/cm at 80 ℃). After the membrane was treated in 1 mol/L NaOH at 80 ℃ for 2 000 h, its conductivity retention was 94.3%, showing good stability. The H₂/O₂ fuel cell assembled with qPTDP?10?CD₅ yielded a peak power density of 1 490 mW/cm² at 80 ℃. In the durability test, the fuel cell assembled with qPTDP?10?CD₅ showed a voltage retention rate of 89.7% after 30 h, showing good cell performance.