With the development of science and technology, the automation and intellectualization of killing technology has become an important direction for the development of oil and gas well control technology. In view of the low efficiency, insufficient safety and imperfect automation of displacement killing, this paper presents a design scheme of automatic displacement killing based on the basic principle and parameter calculation model of displacement killing, and makes sensitivity analysis of the important parameters affecting the killing design. The accuracy of real⁃time monitoring and parameter calculation of automatic killing system directly affects the rationality of killing design. While improving the accuracy of model calculation, we need to configure high⁃accuracy killing monitoring equipment. This scheme can provide some research basis for related researchers and provide some theoretical support for field construction.