Abstract: A new protocol for the photoinduced addition reaction of sulfides with benzophenones has been extablished, affording the αfunctionalized products. The effects of UV wavelength, temperature, concentration of reactants, concentration of Lewis acid catalyst and other factors on the isolated product yield have been investigated. The optimum condition is: UV light wavelength of 313 nm, room temperature, 0.02 mmol of 4,4dimethoxybenzophenone, 0.002 mmol of the catalyst of AlCl3. Under optimum conditions, the isolated yield of the desired product (4methoxyphenyl) (2tetrahydrothienyl) methanol is 57%. Based on the experiment results and corresponding literature reports in this field, a possible mechanism is discussed.

Key words: Organic photochemistry, C—H functionalization, Sulfide, Benzophenone, Green chemistry

摘要：  研究了一种新型的硫醚在紫外光照条件下与二苯甲酮及其衍生物的加成反应, 实现了高效α - 碳氢键官能团化的方法。考察了紫外光波长、 反应温度、 反应物的浓度、 不同L e w i s酸催化剂等因素对产物分离收率的影响, 得出的最佳反应条件为: 紫外光波长为3 1 3n m、 反应温度为室温、 反应物4, 4 ' - 二甲氧基二苯甲酮的物质的量为0. 0 2mm o l 、 L e w i s酸催化剂为A l C l 3。在最佳反应条件下, 目标产物双( 4 - 甲氧基苯基) ( 2 - 四氢噻吩基) 甲醇的分离产率为5 7%, 并探讨了反应的机理。

关键词: 有机光化学, 碳氢键官能团化, 硫醚, 二苯甲酮, 绿色化学