Adsorption of Bilirubin by Carbon Nanotubes with Different Structures

doi:10.3969/j.issn.1672-6952.2021.05.007

Abstract

Abstract:

The bilirubin adsorption properties of three different types of carbon nanotubes (MW, LMW and SW) were studied. X?Ray Diffractomer (XRD) spectra shows that the diameters of the three carbon nanotubes are ranked as LMW>MW>SW. Scanning Electron Microscopy (SEM) and Brunner Emmet Teller (BET) show that MW has the best dispersion, a larger specific surface area, the largest pore size and a maximum pore volume. The bilirubin adsorption results show that the carbon nanotubes have the maximum bilirubin adsorption capacity when the temperature is set as 37^{℃ and the adsorption time reach 40 min. When the concentration of bilirubin is higher than 0.5 g/L, the bilirubin adsorption capacity of MW carbon nanotubes is the largest, and the maximum adsorption capacity of bilirubin reach 208 mg/g membrane. With increasing ion strength, albumin mass concentration, and under alkaline conditions, increasing pH does not benefit the absorption of bilirubin in the buffer solution. Compared with the conventional adsorbents, all the three carbon nanotubes show the excellent performance of short adsorption time and large adsorption capacity for bilirubin, which provide the experimental basis for the preparation of polymer microfiltration membranes blending with carbon nanotubes and its adsorption of bilirubin.}

Key words: Adsorption, Bilirubin, Carbon nanotube, Inorganic materials

摘要：

研究了3种不同型号的碳纳米管（MW、LMW和SW）的胆红素吸附性能。X射线衍射（XRD）谱图显示，3种碳纳米管的管径大小排序为LMW>MW>SW。扫描电子显微镜（SEM）和比表面积测试（BET）结果表明，MW型分散性最好，且具有较大的比表面积、最大的孔径和孔容。胆红素吸附实验结果表明，当温度为37 ℃、吸附时间为40 min时，碳纳米管吸附胆红素的性能最佳。当胆红素质量浓度大于0.5 g/L时，MW型碳纳米管吸附容量最大，最大胆红素吸附量达到208 mg/g。增大NaCl浓度、牛血清白蛋白质量浓度和提高pH均不利于胆红素在溶液中的吸附。与传统吸附剂相比，3种碳纳米管对胆红素均表现出吸附时间短、吸附容量大的优良性能，为后期制备碳纳米管共混微滤膜及其吸附胆红素提供了实验基础。

关键词: 吸附, 胆红素, 碳纳米管, 无机材料

CLC Number:

TE65

Jiayu Tang, Pengfei Kong, Jia Ju, Min Tang, Jianfei Xu, Ling Wang, Sheng Chen. Adsorption of Bilirubin by Carbon Nanotubes with Different Structures[J]. Journal of Liaoning Petrochemical University, 2021, 41(5): 38-43.

汤佳玉, 孔鹏飞, 鞠佳, 唐敏, 徐见飞, 王令, 陈胜. 不同结构碳纳米管吸附胆红素的研究[J]. 辽宁石油化工大学学报, 2021, 41(5): 38-43.

Figures/Tables 10

References 28

1	Houlihan D D， Armstrong M J， Newsome P N. Investigation of Jaundice［J］. Medicine， 2011， 39（9）： 518⁃522.
2	赖芳芳，张丙宏.胆红素对新生儿神经系统影响的研究进展［J］.医学综述， 2018， 24（9）： 1704⁃1708.
3	李孟岩，鞠佳，谢磊，等.PVDF微滤膜的制备、改性及其血液净化应用初探［J］. 辽宁石油化工大学学报， 2019， 39（4）： 7⁃10.
4	Cai N， Li Q， Zhang J， et al. Antifouling zwitterionic hydrogel coating improves hemocompatibility of activated carbon hemoadsorbent［J］. Journal of Colloid and Interface Science， 2017， 503： 168⁃177.
5	Baydemir G， Bereli N， Andac M， et al. Bilirubin recognition via molecularly imprinted supermacroporous cryogels［J］. Colloids and Surfaces B， 2009， 68： 33⁃38.
6	Wu K，Yang W， Liu X， et al. Electrospun porous polyethersulfone （PES） fiber mats with high bilirubin adsorption capacity［J］. Materials Letters， 2016， 185： 252⁃255.
7	Wu K， Yang W， Jiao Y， et al. A Surface molecularly imprinted electrospun polyethersulfone （PES） fiber mat for selective removal of bilirubin［J］. Journal of Materials Chemistry B， 2017， 5（29）： 5763⁃5773.
8	Yola M L， Gode C， Atar N. Molecular imprinting polymer with polyoxometalate/carbon nitride nanotubes for electrochemical recognition of bilirubin［J］. Electrochimica Acta， 2017， 246： 135⁃140.
9	Ma C， Gao Q， Xia K， et al. Three⁃dimensionally porous graphene： A high⁃performance adsorbent for removal of albumin⁃bonded bilirubin［J］. Colloids and Surfaces B， 2017， 149： 146⁃153.
10	Muller B R. Effect of particle size and surface area on the adsorption of albumin⁃bonded bilirubin on activated carbon［J］. Carbon， 2010， 48（12）： 3607⁃3615.
11	Zong W， Chen J， Han W， et al. Preparation of chitosan/amino multiwalled carbon nanotubes nanocomposite beads for bilirubin adsorption in hemoperfusion［J］. Journal of Biomedical Materials Research Part B， 2018， 106（1）： 96⁃103.
12	Ou Y， Gong Q， Liang J. Carbon nanotube⁃chitosan composite beads with radially aligned channels and nanotube⁃exposed walls for bilirubin adsorption［J］. Advanced Engineering Materials， 2015， 17（4）： 460⁃466.
13	Ju J， Liang F， Zhang X， et al. Advancement in separation materials for blood purification therapy［J］. Chinese Journal of Chemical Engineering， 2019， 27（6）： 1383⁃1390.
14	张晖，刘国聪. N掺杂TiO₂纳米膜吸附胆红素分子的石英晶体微天平研究［J］.分析科学学报， 2011， 27（6）： 24⁃29.
15	Yang Z， Si S， Fung Y. Bilirubin adsorption on nanocrystalline titania films［J］. Thin Solid Films， 2007， 515（7/8）： 3344⁃3351.
16	Li Y， Ding J， Luan Z， et al. Competitive adsorption of Pb²⁺， Cu²⁺and Cd²⁺ions from aqueous solutions by multiwalled carbon nanotubes［J］. Carbon， 2003， 41（14）： 2787⁃2792.
17	Wang S， Gao Q， Luo W， et al. Removal of methyl blue from aqueous solution by magnetic carbon nanotube［J］. Water Science and Technology， 2013， 68（3）： 665⁃673.
18	Ramazani S， Ghaedi M， Mortazavi K. Multiwalled carbon nanotubes as efficient adsorbent for the removal of Congo red［J］. Fresenius Environmental Bulletin， 2011， 20（10）： 2514⁃2520.
19	Shinke K， Ando K， Koyama T， et al. Properties of various carbon nanomaterial surfaces in bilirubin adsorption［J］. Colloids and Surfaces B， 2010， 77（1）： 18⁃21.
20	Ju J， He G， Duan Z， et al. Improvement of bilirubin adsorption capacity of cellulose acetate/polyethyleneimine membrane using sodium deoxycholate［J］. Biochemical Engineering Journal， 2013， 79： 144⁃152.
21	鞠佳，聂飞，段志军，等.亲和膜配基的结构和密度对胆红素吸附的影响［J］.化工学报， 2013， 64（1）： 303⁃310.
22	Shi W， Zhang F， Zhang G. Adsorption of bilirubin with polylysine carrying chitosan⁃coated nylon affinity membranes［J］. Journal of Chromatography B， 2005， 819（2）： 301⁃306.
23	Chen J， Ma Y， Wang L， et al. Preparation of chitosan/SiO₂⁃loaded graphene composite beads for efficient removal of bilirubin［J］. Carbon， 2018， 143： 352⁃361.
24	Davies C R， Malchesky P S， Saidel G M. Temperature and albumin effects on adsorption of bilirubin from standard solution using anion⁃exchange resin［J］. Artificial Organs， 1990， 14（1）： 14⁃19.
25	Ando K， Shinke K， Yamada S， et al. Fabrication of carbon nanotube sheets and their bilirubin adsorption capacity［J］. Colloids and Surfaces B， 2009， 71（2）： 255⁃259.
26	Yang Z， Si S， Fung Y. Bilirubin adsorption on nanocrystalline titania films［J］.Thin Solid Films， 2007， 515（7/8）： 3344⁃3351.
27	Shi W， Cao H， Song C， et al. Poly （pyrrole⁃3⁃carboxylic acid）⁃alumina composite membrane for affinity adsorption of bilirubin［J］. Journal of Membrane Science， 2010， 353（1/2）： 151⁃158.
28	Jacobsen J， Brodersen R. Albumin⁃bilirubin binding mechanism［J］. The Journal of Biological Chemistry， 1983， 258（10）： 6319⁃6326.

吸附剂	胆红素最大吸附量/（mg·g^-1）	文献
聚赖氨酸改性尼龙膜	40.7	[22]
TiO₂纳米晶膜	10.0	[26]
β⁃环糊精改性聚醚砜中空纤维膜	51.0	[27]
MW	208.0	本文

吸附剂	胆红素最大吸附量/（mg·g^-1）	文献
聚赖氨酸改性尼龙膜	40.7	[22]
TiO₂纳米晶膜	10.0	[26]
β⁃环糊精改性聚醚砜中空纤维膜	51.0	[27]
MW	208.0	本文

[1]	Jing Zhao, Tianyi Liu, Qiang Li, Xiaoxin Zhang, Yucai Qin, Lijuan Song. Grand Canonical Monte Carlo Simulation of Adsorption and Separation Performances of CO₂/CH₄ by NaX Zeolite [J]. Journal of Liaoning Petrochemical University, 2023, 43(2): 13-19.
[2]	Ping Yang, Youxi Li, Wufeng Cai, Wenbo Liang, Linhai Duan. Preparation of Bimetallic MOF⁃74(Mg _x Ni_1-_x ) and Its Adsorption and Separation Performance for CO₂/N₂ [J]. Journal of Liaoning Petrochemical University, 2022, 42(6): 1-7.
[3]	Yushi Wei, Rui Wang, Zhuang Lin, Heng Jiang, Mingren Huo, Xinyue Chen, Xiaoyan Liang, Chongyang Zhang. Facile Fabrication of Fe₃O₄⁃Based β⁃Cyclodextrin Polymers and Its Adsorption Performances [J]. Journal of Liaoning Petrochemical University, 2022, 42(6): 28-35.
[4]	Shujun Chen, Jianlin Pei, Yue Fu, Yaxue Zhang. Simulation Study on the Adsorption and Diffusion Behavior of Water Molecules in Modified MCM⁃41 [J]. Journal of Liaoning Petrochemical University, 2022, 42(3): 1-7.
[5]	Yongxin Fei, Huiqiang Ma, Shuang Li. Study on Adsorption Performance of Modified Activated Sludge Biochar for Phenol in Water [J]. Journal of Liaoning Petrochemical University, 2022, 42(3): 19-24.
[6]	Siqi Tong, Weiwei Jian, Qiuyan Hai, Weixin Xie, Yi Sun. Research Progress of Porous Solid Materials for CO₂ Adsorption and Removal [J]. Journal of Liaoning Petrochemical University, 2022, 42(2): 30-37.
[7]	Pingyue Zhao, Shuang Li, Fang Zong, Huiqiang Ma. Resource Utilization of Petroleum Resin Wastewater Sludge and Its Phosphorus Adsorption Performance [J]. Journal of Liaoning Petrochemical University, 2021, 41(6): 48-52.
[8]	Xue Wang, Weiwei Jian, Yi Lu, Shaopeng Zhang, Xiaomeng Zhou, Saizhao Han. Adsorption of VOCs Using MWCNTs Modified with Cu and Sn [J]. Journal of Liaoning Petrochemical University, 2021, 41(5): 44-49.
[9]	Mingyan Li, Shuang Cui, Ningning Liu. Adsorption Properties of Methyl Orange by Metal Organic Framework ZIF⁃67 [J]. Journal of Liaoning Petrochemical University, 2021, 41(4): 34-40.
[10]	Zhang Shaopeng， Jian Weiwei， Ma Danzhu， Liu Chao， Wang Xue. Research Progress of Adsorption Properties of Carbon Adsorbents for VOCs [J]. Journal of Liaoning Petrochemical University, 2021, 41(1): 30-36.
[11]	Chen Shujun, Wang Yanfang, Fu Yue, Liu Yongqiang, Wang Zeyuan. Study on Methane Storage Characteristics in MIL⁃101 (Cr) Based on Adsorption⁃Hydration [J]. Journal of Liaoning Petrochemical University, 2020, 40(4): 92-97.
[12]	Qi Yuhuan，Li Jian，Liu Yingying，Yang Lina，Yao Li，Shi Zhewen. Preparation of Hβ/OMC and Adsorption Desulfurization [J]. Journal of Liaoning Petrochemical University, 2019, 39(6): 15-20.
[13]	Wu Zhenyu, Gao Dasheng, Cui Shuang, Xiong Shuang, Liu Ningning, Yao Li, Shi Zhewen. Adsorption Properties of Congo Red from Aqueous Solutions by Porous Polyvinylidene Fluoride Membrane [J]. Journal of Liaoning Petrochemical University, 2019, 39(5): 30-35.
[14]	Li Mengyan，Ju Jia，Xie Lei，Li Leilei，Sun Ran，Yang Lei，Wei Wenshi. Preliminary Study on Preparation, Modification and Blood Purification of PVDF Microfiltration Membrane [J]. Journal of Liaoning Petrochemical University, 2019, 39(4): 7-10.
[15]	Zhu Min，Wang Yanfang，Chen Shujun，Fu Yue，Li Xuejian，Liu Yongqiang. Simulation Study on the Adsorption and Separation of CO2 from Natural Gas by M⁃MOF⁃74 [J]. Journal of Liaoning Petrochemical University, 2019, 39(3): 40-45.