In some areas of Xinjiang, the dip angle of coal seams can reach 50 °. Unlike horizontal coal seams, fluids in high dip coal seams are severely affected by gravity, and the pressure propagation law of coalbed methane wells has special characteristics. The optimal drainage and extraction well position needs to be optimized. This article considers the gravity effect of formation water and establishes a pressure propagation model for single-phase drainage in steep coal seam, and verifies the correctness of the model.Then, the water production of fractured wells in the inclined reservoir is calculated under stable seepage conditions, and the optimal drainage well position is optimized. Finally, numerical simulation methods are used to study the pressure propagation laws of single wells and well groups in heterogeneous bounded inclined reservoirs. The results show that in a high dip coal seam with an inclination angle of 45 °, the position where the distance ratio between the drainage well and the upper and lower boundaries is 3 : 1 is the optimal drainage well position; under the constant pressure drainage mode, there is not much difference in the pressure drop amplitude between the downward and upward tilt directions. In the constant speed depressurization and extraction mode, the pressure drop amplitude in the upward tilt direction is much greater than that in the downward tilt direction.